Fig. 3.

miR-570–3p was a target miRNA of MALAT1 in BC. (A) Schematic diagram of the presumed binding site between MALAT1 and miR-570–3p as well as the sequence of MALAT1 mutant. (B) Luciferase reporter gene assay was used to verify the predicted binding site. (C) The correlation between MALAT1 expression and miR-570–3p expression in BC tissues. (D) miR-570–3p expressions in MALAT1 over-expression and low-expression groups were measured by qRT-PCR. All experiments were performed in triplicate. In (B) and (D), Student's t test was performed; in (C) Pearson's correlation analysis was performed. ∗p < 0.05, ∗∗p < 0.01, and ∗∗∗p < 0.001.