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. 2021 Jan 2;15(2):112–121. doi: 10.1016/j.optom.2020.12.001

Table 3.

Summary of pupil metrics for 1 s and 5 s red and blue stimuli for myopes and non-myopes, along with p-values from the two-way ANOVA illustrating the main effect of wavelength, refractive error and wavelength by refractive error interaction. Metrics include baseline pupil diameter (%), peak constriction (% of baseline), 6 s and 30 s post-illumination pupil response (PIPR, % of baseline) and early and late area under the curve (AUC, unitless). Significant p values (p < 0.05) are highlighted in bold.

Stimulus duration Pupil metrics Wavelength Refractive error
p-values
Myope Non-myope Wavelength Refractive Error Wavelength * refractive error
1 s Baseline Red 100.61 ± 0.61% 101.31 ± 1.26% 0.895 0.855 0.491
Blue 101.05± 0.58% 100.65 ± 0.49%
Peak constriction Red 38.10± 1.35% 35.20 ± 1.85% <0.001 0.172 0.767
Blue 30.35± 1.62% 28.48 ± 2.02%
6 s PIPR Red 81.02± 1.43% 81.01 ± 1.58% <0.001 0.521 0.522
Blue 58.97 ± 3.87% 54.89 ± 4.54%
30 s PIPR Red 97.37± 0.82% 98.98 ± 0.72% <0.001 0.844 0.346
Blue 87.34± 2.06% 84.88 ± 3.60%
Early AUC Red 1.07 ± 0.02 1.05 ± 0.04 <0.001 0.615 0.977
Blue 1.29 ± 0.03 1.27 ± 0.06
Late AUC Red 0.61 ± 0.08 0.59 ± 0.06 <0.001 0.835 0.627
Blue 1.12 ± 0.08 1.18 ± 0.11
5 s Baseline Red 101.10 ± 0.26% 100.85 ± 0.24% 0.905 0.548 0.928
Blue 101.11± 0.43% 100.92 ± 0.44%
Peak constriction Red 19.08±0.95% 20.51 ± 1.71% <0.001 0.188 0.844
Blue 13.32± 0.67% 15.24 ± 1.52%
6 s PIPR Red 74.03± 1.40% 75.09 ± 2.22% <0.001 0.965 0.744
Blue 52.17 ±3.20% 51.37 ± 3.95%
30 s PIPR Red 96.36± 0.70% 97.47 ± 0.78% <0.001 0.401 0.226
Blue 79.30± 3.58% 73.21 ± 4.60%
Early AUC Red 1.18 ± 0.02 1.14 ± 0.03 <0.001 0.286 0.809
Blue 1.35 ± 0.02 1.32 ± 0.04
Late AUC Red 0.72 ± 0.05 0.72 ± 0.07 <0.001 0.665 0.686
Blue 1.28 ± 0.08 1.33 ± 0.08