Table 2.
No healthy behaviours | One healthy behaviour | Two healthy behaviours | Three healthy behaviours | Four healthy behaviours | Five healthy behaviours | p value | ||
---|---|---|---|---|---|---|---|---|
Participants | 14 576 (4·4) | 69 082 (20·9) | 114 086 (34·6) | 90 985 (27·6) | 35 752 (10·8) | 5426 (1·6) | .. | |
Z-standardised leukocyte loge telomere length | −0·07 (1·00) | −0·05 (1·00) | 0·00 (1·00) | 0·04 (1·00) | 0·08 (0·98) | 0·09 (1·01) | 8·80 × 10−135 | |
Age, years | 56·9 (7·7) | 56·7 (7·9) | 56·4 (8·1) | 56·0 (8·1) | 55·8 (8·2) | 56·2 (8·1) | 9·77 × 10−106 | |
Sex | .. | .. | .. | .. | .. | .. | 7·06 × 10−89 | |
Female | 7117 (48·8%) | 33 944 (49·1%) | 58 721 (51·5%) | 48 278 (53·1%) | 19 641 (54·9%) | 2729 (50·3%) | .. | |
Male | 7459 (51·2%) | 35 138 (50·9%) | 55 365 (48·5%) | 42 707 (46·1%) | 16 111 (45·1%) | 2697 (49·7%) | .. | |
Ethnicity | .. | .. | .. | .. | .. | .. | 1·07 × 10−34 | |
White | 13 985 (96·0%) | 65 641 (95·0%) | 107 867 (94·6%) | 86 790 (95·4%) | 34 641 (96·9%) | 5308 (97·8%) | .. | |
Mixed | 82 (0·6%) | 488 (0·7%) | 695 (0·6%) | 490 (0·5%) | 139 (0·4%) | 24 (0·4%) | .. | |
Asian | 194 (1·3%) | 1206 (1·75%) | 2210 (1·9%) | 1555 (1·7%) | 455 (1·3%) | 47 (0·9%) | .. | |
Black | 156 (1·1%) | 1015 (1·5%) | 1910 (1·7%) | 1092 (1·2%) | 231 (0·65%) | 20 (0·4%) | .. | |
Chinese | 10 (0·1%) | 128 (0·2%) | 361 (0·3%) | 384 (0·4%) | 100 (0·28%) | 5 (0·1%) | .. | |
Other | 149 (1·0%) | 604 (0·9%) | 1043 (0·9%) | 674 (0·7%) | 186 (0·5%) | 22 (0·4%) | .. | |
White blood cell count, 109 cells per L | 7·52 (1·91) | 7·18 (1·80) | 6·90 (1·71) | 6·61 (1·61) | 6·37 (1·53) | 6·20 (1·50) | <1·00 × 10−300 | |
Highest education | .. | .. | .. | .. | .. | .. | <1·00 × 10−300 | |
None | 3010 (20·8%) | 12 632 (18·4%) | 17 247 (15·2%) | 10 463 (11·6%) | 2992 (8·4%) | 339 (6·28%) | .. | |
O levels or CSE | 2681 (18·5%) | 12 301 (17·9%) | 19 178 (16·9%) | 14 199 (15·7%) | 4883 (13·7%) | 628 (11·6%) | .. | |
A levels, NVQ, other | 4921 (34·0%) | 23 561 (34·3%) | 39 050 (34·5%) | 30 031 (33·2%) | 10 856 (30·5%) | 1530 (28·3%) | .. | |
Degree | 3866 (26·7%) | 20 122 (29·3%) | 37 803 (33·4%) | 35 757 (39·5%) | 16 868 (47·4%) | 2904 (53·8%) | .. | |
Insomnia | .. | .. | .. | .. | .. | .. | <1·00 × 10−300 | |
Never or rarely | 2944 (20·2%) | 15 830 (22·9%) | 28 646 (25·1%) | 24 383 (26·8%) | 10 233 (28·6%) | 1614 (29·8%) | .. | |
Sometimes | 6383 (43·8%) | 32 117 (46·5%) | 54 068 (47·4%) | 44 052 (48·4%) | 17 319 (48·5%) | 2620 (48·3%) | .. | |
Usually | 5242 (36·0%) | 21 099 (30·6%) | 31 330 (27·5%) | 22 519 (24·8%) | 8186 (22·9%) | 1189 (21·9%) | .. | |
Fed-up feelings | 7370 (51·4%) | 30 178 (44·4%) | 44 511 (39·6%) | 31 560 (35·3%) | 11 058 (31·4%) | 1480 (27·6%) | <1·00 × 10−300 | |
LDL cholesterol, mmol/L | 3·6 (0·9) | 3·59 (0·9) | 3·6 (0·9) | 3·6 (0·8) | 3·5 (0·8) | 3·4 (0·8) | 3·68 × 10−69 | |
C-reactive protein, mg/L | 3·9 (4·7) | 3·1 (4·0) | 2·6 (3·6) | 2·0 (3·1) | 1·5 (2·9) | 1·3 (2·6) | <1·00 × 10−300 | |
Estimated glomerular filtration rate, mg/dL | 71·2 (76·2) | 71·2 (75·8) | 74·0 (75·3) | 76·2 (74·5) | 78·6 (73·6) | 71·9 (73·3) | 8·11 × 10−62 | |
Diabetes | 1618 (11·1%) | 4907 (7·1%) | 6051 (5·3%) | 3057 (3·4%) | 697 (1·95%) | 80 (1·5%) | <1·00 × 10−300 | |
Cancer | 1257 (8·7%) | 5339 (7·8%) | 8602 (7·7 %) | 6491 (7·2 %) | 2566 (7·2 %) | 383 (7·1%) | 1·99 × 10−11 | |
Hypertension | 5563 (38·2%) | 22 847 (33·1%) | 32 234 (28·3%) | 19 927 (21·9%) | 5728 (16·0%) | 780 (14·4%) | <1·00 × 10−300 | |
Vascular disease | 1541 (10·6%) | 5225 (7·6%) | 6532 (5·7%) | 3590 (4·0%) | 1081 (3·0%) | 161 (3·0%) | <1·00 × 10−300 |
Data are mean (SD) or n (%). Diseases are self-reported as diagnosed by doctor. p values were estimated with the Jonckheere-Terpstra test for trend for both continuous and categorical traits.