Table 5. Logistic regression for combined vascular events at one year in the full model when introducing all variables as binary variables.

	Reference	Adjusted HR* (95% CI)	P-value
*Referred to adjust for all variants included in each model using stepwise regression analysis method. CI: confidence interval; HR: hazard ratio; NIHSS: National Institutes of Health Stroke Scale.
Model 1
Essen score ≥ 3	Essen score (0–2)	1.32 (1.18–1.48)	< 0.001
NIHSS score ≥ 4	NIHSS score (0–3)	1.33 (1.19–1.49)	< 0.001
Large artery atherosclerosis	No large artery atherosclerosis	1.32 (1.17–1.50)	< 0.001
Multiple acute infarction	Single acute infarction or no infarction	1.34 (1.19–1.51)	< 0.001
Model 2
Essen score ≥ 3	Essen stroke risk score (0–2)	1.33 (1.19–1.49)	< 0.001
NIHSS score ≥ 4	NIHSS score (0–3)	1.30 (1.16–1.45)	< 0.001
Large artery atherosclerosis	No large artery atherosclerosis	1.43 (1.27–1.61)	< 0.001
Acute infarctions	No infarction	1.63 (1.31–2.03)	< 0.001
Model 3
Essen score ≥ 3	Essen stroke risk score (0–2)	1.33 (1.19–1.49)	< 0.001
NIHSS score ≥ 4	NIHSS score (0–3)	1.30 (1.16–1.46)	< 0.001
No infarction with large artery atherosclerosis	No infarction without large artery atherosclerosis	1.51 (0.96–2.38)	0.077
Acute infarctions without large artery 　atherosclerosis	No infarction without large artery atherosclerosis	1.66 (1.28–2.14)	< 0.001
Acute infarctions with large artery 　atherosclerosis	No infarction without large artery atherosclerosis	2.37 (1.81–3.09)	< 0.001