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. 2022 May 4;13:2457. doi: 10.1038/s41467-022-29986-y

Fig. 2. Condition optimization.

Fig. 2

Reactions in this table were performed on a 0.1 mmol scale. Yields and d.r. values were determined by 1H NMR spectroscopy of the crude reaction mixture with 1,1,2,2-tetrachloroethane as an internal standard. The ee values were determined by HPLC analysis. a10a (1.5 equiv.) and 11a (1.0 equiv.) were used. bThe ratio of ligand to Cu is 1:1.