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. 2022 May 4;12:7297. doi: 10.1038/s41598-022-11064-4

Table 3.

Cases with discordant results between intraoperative pathological diagnosis and OSNA assay.

Patient no. Histological type Lymph node station IPD/OSNA* CK19 mRNA (copies/μl)
4 Sq 11 (interlobar node) Negative/micro 2700
15 Ad 11s (interlobar node) Negative/micro  < 250**
77 Ad 7 (subcarinal node) Positive/Negative  < 250
10L (hilar node) Positive/negative  < 250
94 Ad 11 (interlobar node) Negative/negative 270

Sq, squamous cell carcinoma; Ad, adenocarcinoma; IPD, interoperative pathological diagnosis.

*In the OSNA assay, macro, micro, and negative showed > 5000, 250–5000, and < 250 copies/uL of CK19 mRNA, respectively.

**Micrometastasis detected in diluted sample.