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. 2022 May 4;79(5):281. doi: 10.1007/s00018-022-04296-0

Fig. 8.

Fig. 8

Ser218 can move closer to ATP when B-Raf Arg662 moves to the outside of the N-terminal helix of the A-loop in MEK1. a Distance between Ser222 and ATP (d1) minus the distance between Ser218 and ATP (d2). Positive values indicate that Ser222 is closer to ATP than Ser218. b Distance between Arg662 and Ser222 (d3) minus the distance between Arg662 and Ser218 (d4). Positive values indicate Arg662 is inside the A-loop of MEK1. Bottom: diagram indicating the distances measured in (a, b)