Table 2.
Model/time point | Acan | Vcan | Ncan | Ptprz1 |
---|---|---|---|---|
wildtype/P10 | 1.01 ± 0.13 | 1.21 ± 0.45 | 1.02 ± 0.15 | 1.02 ± 0.14 |
wildtype/P14 | 1.44 ± 0.06 | 0.56 ± 0.24 | 0.36 ± 0.10 | 0.41 ± 0.02 |
wildtype/3 weeks | 2.35 ± 0.49 | 0.81 ± 0.37 | 0.15 ± 0.04 | 0.17 ± 0.03 |
wildtype/6 weeks | 0.99 ± 0.16 | 1.23 ± 0.03 | 0.01 ± 0.01 | 0.07 ± 0.02 |
wildtype/3 months | 1.02 ± 0.05 | 0.08 ± 0.00 | 0.03 ± 0.01 | 0.04 ± 0.00 |
wildtype/6 months | 0.85 ± 0.07 | 0.09 ± 0.01 | 0.02 ± 0.01 | 0.03 ± 0.01 |
Aipl1-/-/P10 | 0.87 ± 0.06 | 0.72 ± 0.37 | 0.99 ± 0.23 | 0.72 ± 0.12 |
Aipl1-/-/P14 | 2.27 ± 0.35 | 1.68 ± 0.59 | 0.36 ± 0.16 | 0.66 ± 0.12 |
Aipl1-/-/3 weeks | 3.67 ± 0.45 | 1.47 ± 0.68 | 0.16 ± 0.05 | 0.28 ± 0.04 |
Pde6brd1/rd1/P10 | 0.62 ± 0.13 | 0.53 ± 0.08 | 0.47 ± 0.14 | 0.58 ± 0.02 |
Pde6brd1/rd1/3 weeks | 2.81 ± 0.37 | 1.32 ± 0.64 | 0.02 ± 0.00 | 0.15 ± 0.04 |
Pde6brd1/rd1/6–7 weeks | 5.34 ± 0.08 | 0.23 ± 0.07 | 0.07 ± 0.04 | 0.05 ± 0.00 |
Rho-/-/P10 | 1.75 ± 0.30 | 0.60 ± 0.01 | 0.23 ± 0.13 | 0.55 ± 0.10 |
Rho-/-/3–4 weeks | 2.29 ± 0.25 | 0.49 ± 0.09 | 0.08 ± 0.01 | 0.07 ± 0.01 |
Rho-/-/6 weeks | 1.71 ± 0.04 | 0.27 ± 0.01 | 0.09 ± 0.02 | 0.07 ± 0.01 |
Rho-/-/3 months | 1.58 ± 0.04 | 0.37 ± 0.02 | 0.10 ± 0.02 | 0.08 ± 0.01 |
Data shown is fold change ± SEM, relative to wildtype at P10.