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. 2022 May 4;13:2451. doi: 10.1038/s41467-022-30051-x

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — a Age distribution by health network of sample collection within the University of California, San Francisco (UCSF) (N = 698 biologically independent samples) and San Francisco Department of Public Health (ZSFG) hospital networks (N = 316 biologically independent samples). Each point represents a sample and colors correspond to age bins used for analysis. The box plot whiskers show the maximum and minimum ages, the box shows the 25-75^th percentile values for age, and the central line within the boxplot represents the median age within each health network. b Proportion of samples from a given San Francisco zipcode plotted against the proportion of the San Francisco population within that zipcode. Colors show the percentage of residents below the poverty line within that zipcode, as determined by the American Community Survey 2019¹⁵, using census bureau definitions of poverty thresholds³⁵.