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. 2022 May 4;12:7251. doi: 10.1038/s41598-022-11291-9

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Tremor scores pre- and postoperatively without DBS. (A) Parkinsonian (PD) patients were assessed by the tremor items of the UPDRS preoperatively in Med OFF and Med ON condition as well as postoperatively in Med ON STIM OFF. (B) Essential tremor (ET) patients were assessed pre- and postoperatively in Med OFF condition by the FTMRS. In STIM OFF, PD tremor remained stable, whereas the tremor intensity in ET worsened during the postoperative course indicating natural disease progression. **Significance level of p < 0.01. Figure was created with GraphPad Prism (version 9 for Windows, La Jolla, USA).