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. 2022 May 4;12:7251. doi: 10.1038/s41598-022-11291-9

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Comparison of new DBS stimulation modes between PD and ET patients. (A) Tremor score was normalized to the OFF FTMRS-Score. Both oDBS60 and oDBS30 at the dorsal contact reduced tremor in PD more than in ET patients. (B) Difference between the ataxia sum score at oDBS60 and the new DBS stimulation modes oDBS30 and dDBS60 at the corresponding electrode. In PD patients, oDBS30 reduced ataxia more than in ET patients at the ventral stimulation level. There was no significant difference for oDBS30 dorsal and dDBS60. Asterisks indicate the different significance levels *p < 0.05, **p < 0.01, ***p < 0.001). Figure was created with GraphPad Prism (version 9 for Windows, La Jolla, USA).