Fig. 3.

Characterization of the analgesic effect of SCS in a rat model of neuropathic pain. A, B Time courses for changes in impedance A and motor threshold B after SCS electrode implantation. C1 The 50% PWT in rats with severe and moderate mechanical hypersensitivity during and after 30-min 50-Hz spinal cord stimulation. C2 The mean 50% PWT calculated from C1. Pre-SCS, 50% PWT at 0 min in C1; Dur-SCS, mean 50% PWT at 15 and 30 min in C1; Post-SCS, 50% PWT at 60 min in C1. Repeated ANOVA with Dunnett's multiple comparisons test; **P < 0.01 vs Pre-SCS; ^###P < 0.001 vs 50% PWT in Dur-SCS between moderate and severe mechanical hypersensitivity.