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CTOP and SCS experimental design [21] i.t.
| Stage 1 | Stage 2 | Stage 3 | ||||||
|---|---|---|---|---|---|---|---|---|
| Antagonist | SCS (Hz) | Time | Antagonist CTOP (μg) |
SCS (Hz) |
Time | Antagonist CTOP (μg) |
SCS (Hz) | Time |
| Vehicle (10 μL) | 2 | Day 8 | 3 | 2 | Day 11 | 10 | 2 | Day 14 |
| 100 | Day 9 | 10 | 100 | Day 12 | 30 | 100 | Day 15 | |
| 10 k | Day 10 | 10 | 10 k | Day 13 | 30 | 10 k | Day 16 | |
