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. 2022 Apr 21;10:814250. doi: 10.3389/fcell.2022.814250

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Copyright © 2022 Lovely, Duerr, Qiu, Galvan, Voss and Monaghan.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Limb regeneration after Wnt inhibition. (A) Quantification of limb growth after C59 treatment starting at 3 dpa. Treated limbs were smaller than control limbs at 8 dpa (p = 0.0092; Student’s t-test) and 12 dpa (p = 0.0031; Student’s t-test). (B) Limb regeneration of untreated (DMSO) and treated (C59) limbs 1 month after removal from C59 (12 dpa).