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. 2022 Apr 21;13:848529. doi: 10.3389/fphar.2022.848529

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Copyright © 2022 Chen, Cai, Zhu, Wang, Gao, Yang, Mao, Zhang and Sun.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Edaravone dexborneol treatment improves sensorimotor functions after SAH. (A) Neurological scores were determined 1–10 days after SAH with the modified Garcia scoring system. (B–D) Acute sensorimotor dysfunction at 1–21 days after SAH was assessed by (A) Garcia score, (B) rotarod test, (C) foot-fault test, and (D) corner test. N = 8/group. Data are given as mean ± SE. *p < 0.05, **p < 0.01, ***p < 0.001 vs. Eda. ^### p < 0.001, ^#### p < 0.0001 vs. PBS. Eda: edaravone; Eda dexborneol: edaravone dexborneol.