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. 2022 Apr 21;13:848529. doi: 10.3389/fphar.2022.848529

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Copyright © 2022 Chen, Cai, Zhu, Wang, Gao, Yang, Mao, Zhang and Sun.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Western blot showing that edaravone dexborneol treatment profoundly decreased the levels of cleaved caspase 3 in the brain after SAH injury. (A,B) Representative Western blot images and semiquantitative data show the expression of cleaved caspase 3 in the basal cortex (A) and CA1 hippocampus (B) at 3 d after SAH. Data are normalized to sham. n = 4/group. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001. Eda: edaravone; Eda dexborneol: edaravone dexborneol.