TABLE 1.
Effects of P2Y14 shRNA and naringin on heart rate and blood pressure in rats.
| Group | Heart rate (beat/min) | Blood pressure | ||
|---|---|---|---|---|
| SBP (mm Hg) | DBP (mm Hg) | MBP (mm Hg) | ||
| Control | 322.70 ± 2.02 | 113.00 ± 1.81 | 87.10 ± 1.99 | 95.50 ± 1.87 |
| DM | 382.80 ± 2.43** | 142.90 ± 1.88** | 97.00 ± 1.29** | 112.40 ± 1.42** |
| DM + P2Y14 shRNA | 325.20 ± 1.95## | 119.90 ± 1.33## | 86.00 ± 1.39## | 97.30 ± 1.10## |
| DM + NC shRNA | 385.50 ± 2.51** | 144.30 ± 2.00** | 98.10 ± 2.08** | 113.30 ± 2.01** |
| DM + naringin | 325.60 ± 2.00## | 117.20 ± 1.90## | 87.90 ± 1.55## | 97.70 ± 1.38## |
| DM + PBS | 385.70 ± 2.15** | 144.80 ± 1.63** | 97.20 ± 1.69** | 112.90 ± 1.65** |
HR, heart rate; SBP, systolic blood pressure; DBP, diastolic blood pressure; MBP, mean blood pressure. Values are the mean ± SEM from ten observations in each group. **p < 0.01 vs. Ctrl; ##p < 0.01 vs. DM.