Table 4.

Evaluation of experiments to investigate drifts between internal and external data.

	Liver toxicity			Micro nucleus test
	CV	Predict holdout set		CV	Predict holdout set
		Cal_original	Cal_update		Cal_original	Cal_update
Balanced validity	0.81	0.47	0.82	0.82	0.50	0.74
Balanced efficiency	0.81	0.89	0.38	0.79	0.94	0.40
Balanced accuracy	0.77	0.43	0.49	0.77	0.49	0.39
Validity inactive class	0.81	0.75	0.84	0.80	0.99	0.61
Efficiency inactive class	0.84	0.84	0.45	0.79	0.89	0.54
Accuracy inactive class	0.77	0.70	0.63	0.75	0.99	0.29
Validity active class	0.82	0.20	0.80	0.83	0.00	0.88
Efficiency active class	0.78	0.95	0.31	0.79	1.00	0.26
Accuracy active class	0.77	0.16	0.35	0.78	0.00	0.50
Validity	0.82	0.58	0.84	0.81	0.66	0.70
Efficiency	0.80	0.87	0.40	0.79	0.93	0.45
Accuracy	0.77	0.52	0.57	0.76	0.63	0.33