Table 3.

Univariate and multiple logistic regression analyses of factors associated with relevant response to nalfurafine hydrochloride.

Factor	Univariate analysis			Multivariate analysis
	OR	95%CI	P value	OR	95%CI	P value
Age	1.00	0.98–1.02	0.44
Body weight	1.01	0.99–1.03	0.96
Itching period	0.97	0.96–0.99	1.15 × 10–2	0.95	0.93–0.98	2.95 × 10–3
Baseline VAS	1.01	0.99–1.03	0.46
Child–Pugh Class C (vs. A and B)	0.40	0.22–0.74	3.47 × 10–2
Hepatocellular carcinoma (presence)	1.36	0.73–2.54	0.34
Platelet	1.01	0.98–1.04	0.37
PT	1.00	0.99–1.01	0.73
AST	0.99	0.98–1.00	0.07
ALT	1.00	0.99–1.00	0.26
Total bilirubin	0.91	0.85–0.99	2.25 × 10–2
Creatinine	1.06	0.91–1.23	0.46
FIB-4 index	0.95	0.90–1.01	0.09
ALBI score	0.78	0.59–1.05	0.10

OR odds ratio, CI confidence interval, VAS Visual Analog Scale, AST aspartate aminotransferase, ALT alanine aminotransferase, FIB-4 fibrosis-4.