Table 2.
Significantly differentially metabolites in small intestine by comparison of the LRFI and HRFI groups.1
| Small intestine | Processes | Metabolites | Formula | VIP2 | p3 | FC4 | Trend5 |
|---|---|---|---|---|---|---|---|
| Duodenum | Protein digestion and absorption | L-Glutamate | C5H9NO4 | 1.26 | p < 0.02 | 1.09 | Up |
| L-Tyrosine | C9H11NO3 | 1.37 | p < 0.02 | 1.05 | Up | ||
| Beta-alanine | C3H7NO2 | 1.48 | p < 0.03 | 1.20 | Up | ||
| Glycerophospholipid metabolism | PC (18:2(9Z,12Z)/20:4(5Z,8Z,11Z,14Z)) | C46H80NO8P | 1.34 | p < 0.03 | 1.11 | Up | |
| Phosphocholine | C5H14NO4P | 1.35 | p < 0.03 | 1.14 | Up | ||
| Choline | C5H13NO | 1.32 | p < 0.04 | 1.06 | Up | ||
| Jejunum | Protein digestion and absorption | L-Glutamate | C5H9NO2 | 1.50 | p < 0.01 | 1.08 | Up |
| L-Serine | C5H10N2O3 | 1.36 | p < 0.01 | 1.14 | Up | ||
| L-Methionine | C5H11NO2S | 1.51 | p < 0.01 | 1.05 | Up | ||
| L-Histidine | C6H9N3O2 | 1.21 | p < 0.03 | 1.05 | Up | ||
| L-Aspartic acid | C4H7NO4 | 1.38 | p < 0.01 | 1.13 | Up | ||
| L-Isoleucine | C6H13NO2 | 1.51 | p < 0.01 | 1.04 | Up | ||
| L-Tyrosine | C9H11NO3 | 1.31 | p < 0.01 | 1.03 | Up | ||
| Glycerophospholipid metabolism | PC (18:2(9Z,12Z)/20:4(5Z,8Z,11Z,14Z)) | C46H80NO8P | 1.38 | p < 0.02 | 1.46 | Up | |
| PS (18:0/20:4(8Z,11Z,14Z,17Z)) | C44H78NO10P | 1.15 | p < 0.05 | 1.39 | Up | ||
| Choline | C5H13NO | 1.48 | p < 0.01 | 1.13 | Up | ||
| lleum | Protein digestion and absorption | L-Glutamate | C5H9NO4 | 1.16 | p < 0.04 | 1.06 | Up |
| L-Serine | C3H7NO3 | 1.25 | p < 0.01 | 1.15 | Up | ||
| Beta-alanine | C3H7NO2 | 1.18 | p < 0.01 | 1.07 | Up | ||
| L-Aspartic acid | C4H7NO4 | 1.21 | p < 0.01 | 1.09 | Up | ||
| L-Lysine | C6H14N2O2 | 1.21 | p < 0.01 | 1.43 | Up | ||
| Glycerophospholipid metabolism | PC (18:2(9Z,12Z)/20:4(5Z,8Z,11Z,14Z)) | C46H80NO8P | 1.23 | p < 0.03 | 1.08 | Up | |
| LysoPC (20:4(8Z,11Z,14Z,17Z)) | C28H50NO7P | 1.31 | p < 0.01 | 1.34 | Up | ||
| LysoPC (20:4(5Z,8Z,11Z,14Z)) | C28H50NO7P | 1.25 | p < 0.01 | 1.07 | Up | ||
| LysoPC (20:2(11Z,14Z)) | C28H54NO7P | 1.17 | p < 0.04 | 1.16 | Up | ||
| LysoPC (18:1(11Z)) | C26H52NO7P | 1.37 | p < 0.01 | 1.10 | Up | ||
| LysoPC (18:1(9Z)) | C26H52NO7P | 1.41 | p < 0.01 | 1.13 | Up | ||
| LysoPC (16:0) | C24H50NO7P | 1.23 | p < 0.02 | 1.09 | Up | ||
| LysoPC (18:0) | C26H54NO7P | 1.15 | p < 0.04 | 1.11 | Up | ||
| LysoPC (22:0) | C30H62NO7P | 1.41 | p < 0.01 | 1.43 | Up | ||
| Choline | C5H13NO | 1.39 | p < 0.01 | 1.09 | Up | ||
| Phosphocholine | C5H14NO4P | 1.40 | p < 0.01 | 1.89 | Up |
1
LRFI, Low residual feed intake and HRFI, high residual feed intake.
2
VIP, Variable importance in the projection.
3
Value of p (false discovery rate) are derived using a Student’s t-test to assess the diferences between the HRFI group and the LRFI group; significance was considered at p < 0.05.
4
FC, Fold change.
5
Up, upregulated and down, downregulated.