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. 2022 Apr 21;12:870636. doi: 10.3389/fonc.2022.870636

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Copyright © 2022 Chen, Jia, Zhang and Zhang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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MA and GE synergistically inhibited the expression of BCRP and MRP7. BCRP and MRP7 in PC9/GR (A) and H292/GR (B) cells. (C, D) The membrane protein expression of BCRP and MRP7 in PC9/GR and H292/GR cells after MA and GE for single or in combination exposed. (E, F) The total cell lysate protein expression of BCRP and MRP7 in PC9/GR and H292/GR cells after MA and GE for single or in combination exposed. Data are presented for at least three independent repetitions and were illustrated as mean ± SD. *p < 0.05.