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. 2022 Apr 21;12:886404. doi: 10.3389/fonc.2022.886404

Table 2.

Descriptive analysis of clinical evolution of OPMDs.

Patient number (n = 106) Characteristics Number (%)
First Local Recurrence Yes 40 (37.7)
OPMDs 22 (20.7)
OSCC 18 (17.0)
No 66 (62.3)
Further Local Recurrence (among patients with first recurrence of OPMDs) (n = 22) Yes 9 (40.9)
OPMDs 2 (9.0)
OSCC 7 (31.8)
No 13 (59.1)
Overall OPMDs Recurrence Yes 24 (22.6)
No 82 (77.4)
Patients number (n = 24)
OPMDs Recurrence Subsite Tongue 17 (68.8)
Cheek 6 (30.3)
Other 1 (0.9)
OPMDs First Recurrence Grading SIN1/SIN2 20 (81.8)
SIN3-CIS 4 (18.2)
Overall Malignant Transformation Yes 25 (23.5)
No 81 (76.0)
Patient number (n = 25)
OSCC Site Tongue 10 (40.0)
Cheek 9 (36.0)
Other 6 (24.0)
OSCC Grading G1 9 (36.0)
G2 12 (48.0)
G3 4 (16.0)
OSCC TNM (AJCC VIII edition)
 T T1 17 (68.0)
 N T>1 8 (21.0)
 M N0 21 (84.0)
N>1 4 (16.0)
M0 25 (100.0)
OSCC Treatment Surgery 20 (80.0)
Surgery + Radiotherapy 5 (20.0)

OPMDs, oral potentially malignant disorders; OSCC, oral squamous cell carcinoma; SIN, squamous intraepithelial neoplasia; CIS, carcinoma in situ; TNM, tumor-node-metastasis; AJCC, American Joint Committee of Cancer.