Table. Age-Standardized and Projected Mortality Rates of Alcohol Use Disorder–Related Mortality Stratified by Decedent Age Group and Sex, 2012 to 2021.
| Variable | Age-standardized mortality rate per 100 000 persons | |||||||
|---|---|---|---|---|---|---|---|---|
| 2012 Observed |
2019 Observed |
2020 | 2021 | |||||
| Observed | Projected (95% CI) | % Differencea | Observed | Projected (95% CI) | % Differencea | |||
| AUD-related mortality | ||||||||
| Multiple causes of death | 10.63 | 15.11 | 19.68 | 15.77 (15.38-16.15) | +24.79 | 20.00 | 16.40 (15.99-16.82) | +21.95 |
| Multiple causes of death (non–COVID-19)b | 10.63 | 15.11 | 19.34 | 15.77 (15.38-16.15) | +22.64 | 19.48 | 16.40 (15.99-16.82) | +18.78 |
| Underlying cause of deathc | 3.05 | 4.57 | 6.21 | 4.75 (4.58-4.92) | +30.74 | 6.40 | 4.97 (4.78-5.15) | +28.77 |
| Age, y | ||||||||
| 25-44 | 4.55 | 7.43 | 10.83 | 7.71 (7.17-8.25) | +40.47 | 10.85 | 8.10 (7.52-8.68) | +33.95 |
| 45-64 | 17.14 | 23.00 | 29.21 | 24.01 (23.28-24.74) | +21.66 | 28.95 | 24.84 (24.06-25.62) | +16.55 |
| ≥65 | 13.53 | 19.40 | 23.83 | 20.31 (19.48-21.14) | +17.33 | 25.83 | 21.19 (20.30-22.08) | +21.90 |
| Sex | ||||||||
| Women | 4.47 | 6.77 | 8.85 | 7.10 (6.96-7.23) | +24.65 | 8.91 | 7.42 (7.28-7.57) | +20.08 |
| Men | 17.37 | 24.15 | 31.35 | 25.15 (24.48-25.83) | +24.65 | 31.96 | 26.11 (25.39-26.84) | +22.41 |
| Referent | ||||||||
| All-cause mortality | 1097.84 | 1071.78 | 1254.44 | 1077.69 (1056.87-1098.50) | +16.40 | 1271.54 | 1074.99 (1052.68-1097.30) | +18.28 |
Abbreviation: AUD, alcohol use disorder.
a
Percentage differences were calculated as follows: (Observed – Projected)/Projected × 100%.
b
Excluded decedents with COVID-19 infection as the underlying cause of death.
c
Included decedents with AUD listed as the primary cause of death.