Table 2.
Significant variables in univariate analysis.
| Characteristics | Without MACEa (n=753) | With MACE (n=251) | Statisticb | df | P value | ||||
| Age (years), mean (SD) | 63.47 (10.98) | 66.82 (11.10) | –4.180 | 1002 | <.001 | ||||
| Smoking, n (%) | 4.360 | 1 | .04 | ||||||
|
|
No | 429 (57.0) | 124 (49.4) |
|
|
|
|||
|
|
Yes | 324 (43.0) | 127 (50.6) |
|
|
|
|||
| Type of work, n (%) | 6.213 | 1 | .013 | ||||||
|
|
Physical work | 353 (46.9) | 95 (37.8) |
|
|
|
|||
|
|
Mental work | 400 (53.1) | 156 (62.2) |
|
|
|
|||
| Course of disease (years since diagnosis), mean (SD) | 3.41 (5.11) | 5.43 (5.81) | –4.930 | 387.17 | <.001 | ||||
| Family history, n (%) | 4.387 | 1 | .04 | ||||||
|
|
No | 693 (92.0) | 220 (87.6) |
|
|
|
|||
|
|
Yes | 60 (8.0) | 31 (12.4) |
|
|
|
|||
| Seasonal onset, n (%) | 17.920 | 1 | <.001 | ||||||
|
|
No obvious seasonality | 675 (89.6) | 199 (79.3) |
|
|
|
|||
|
|
Obvious seasonality | 78 (10.4) | 52 (20.7) |
|
|
|
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| Previous myocardial infarction, n (%) | 80.775 | 1 | <.001 | ||||||
|
|
No | 643 (85.4) | 147 (58.6) |
|
|
|
|||
|
|
Yes | 110 (14.6) | 104 (41.4) |
|
|
|
|||
| Dyslipidemia, n (%) | 6.659 | 1 | .01 | ||||||
|
|
No | 681 (90.4) | 240 (95.6) |
|
|
|
|||
|
|
Yes | 72 (9.6) | 11 (4.4) |
|
|
|
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| Brain infarction, n (%) | 24.822 | 1 | <.001 | ||||||
|
|
No | 671 (89.1) | 192 (76.5) |
|
|
|
|||
|
|
Yes | 82 (10.9) | 59 (23.5) |
|
|
|
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| Cardiac insufficiency, n (%) | 6.249 | 1 | .01 | ||||||
|
|
No | 712 (94.6) | 226 (90.0) |
|
|
|
|||
|
|
Yes | 41 (5.4) | 25 (10.0) |
|
|
|
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| TCM c treatment, n (%) | 4.489 | 1 | .03 | ||||||
|
|
No | 570 (75.7) | 173 (68.9) |
|
|
|
|||
|
|
Yes | 183 (24.3) | 78 (31.1) |
|
|
|
|||
| Anticoagulant drugs, n (%) | 47.408 | 1 | <.001 | ||||||
|
|
No | 367 (48.7) | 185 (73.7) |
|
|
|
|||
|
|
Yes | 386 (51.3) | 66 (26.3) |
|
|
|
|||
| Antiarrhythmic drugs, n (%) | 4.123 | 1 | .04 | ||||||
|
|
No | 703 (93.4) | 243 (96.8) |
|
|
|
|||
|
|
Yes | 50 (6.6) | 8 (3.2) |
|
|
|
|||
| Diuretic, n (%) | 6.055 | 1 | .01 | ||||||
|
|
No | 636 (84.5) | 195 (77.7) |
|
|
|
|||
|
|
Yes | 117 (15.5) | 56 (22.3) |
|
|
|
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| Lansoprazole injection, n (%) | 14.381 | 1 | <.001 | ||||||
|
|
No | 634 (84.2) | 235 (93.6) |
|
|
|
|||
|
|
Yes | 119 (15.8) | 16 (6.4) |
|
|
|
|||
| Bleeding events, n (%) | 12.446 | 1 | <.001 | ||||||
|
|
No | 735 (97.6) | 233 (92.8) |
|
|
|
|||
|
|
Yes | 18 (2.4) | 18 (7.2) |
|
|
|
|||
| LADd (mm), mean (SD) | 36.59 (4.91) | 37.70 (5.54) | –2.988 | 1002 | .003 | ||||
| LVEFe (%), mean (SD) | 52.65 (8.08) | 51.31 (8.91) | 2.113 | 395.97 | .04 | ||||
| Bypass surgery, n (%) | 7.200 | 1 | .007 | ||||||
|
|
No | 745 (98.9) | 242 (96.4) |
|
|
|
|||
|
|
Yes | 8 (1.1) | 9 (3.6) |
|
|
|
|||
| HAMDf, mean (SD) | 7.23 (5.26) | 9.27 (5.87) | –4.877 | 392.12 | <.001 | ||||
| HAMAg, mean (SD) | 8.23 (6.59) | 11.13 (6.83) | –5.979 | 1002 | <.001 | ||||
aMACE: major adverse cardiovascular events.
bt statistics for continuous variable comparisons and χ2 statistics for categorical variables.
cTCM: traditional Chinese medicine.
dLAD: left atrial diameter.
eLVEF: left ventricular ejection fraction.
fHAMD: Hamilton depression scale.
gHAMA: Hamilton anxiety scale.