Table 1.
List of clinical trials about natural products combined with cancer immunotherapy.
| NCT number | Natural product | Caner immunotherapy | Disease | Status | Phase |
|---|---|---|---|---|---|
| NCT03192059 | Curcumin | Pembrolizumab | Cervical cancer/Endometrial cancer/Uterine cancer | Recruiting | II |
| NCT00470574 | QS-21 | Sialyl lewisa-keyhole limpet hemocyanin conjugate vaccine | Breast cancer | Completed | – |
| NCT00036933 | QS-21 | MUC-2-Globo H-KLH conjugate vaccine | Prostate cancer | Completed | I |
| NCT00004929 | QS-21 | MUC-2-KLH vaccine | Prostate cancer | Completed | I |
| NCT00005632 | QS-21 | MUC1-KLH vaccine | Prostate cancer | Completed | I |
| NCT00003357 | OS-21 | GM2-KLH vaccine | Breast cancer | Completed | I |
| NCT00003819 | QS-21 | TF(c)-KLH conjugate vaccine | Prostate cancer | Completed | I |
| NCT00004156 | QS-21 | MUC1-KLH vaccine | Breast cancer | Completed | I |
| NCT00030823 | QS-21 | Globo-H-GM2-Lewis-y-MUC1-32(aa)-sTn(c)-Tn(c)-KLH conjugate vaccine | Breast cancer | Completed | – |
| NCT00006041 | QS-21 | MUC1-KLH vaccine | Fallopian tube cancer/Ovarian cancer/Primary peritoneal cavity cancer | Completed | I |
| NCT00006387 | QS-21 | Ras-peptide cancer vaccine | Colorectal cancer/Pancreatic cancer | Completed | I |
| NCT00001572 | QS-21 | Id-KLH vaccine | B cell lymphoma/Follicular lymphoma/Neoplasm | Completed | I |
| NCT00004052 | QS-21 | BCR‒ABL peptide vaccine | Leukemia | Completed | II |
| NCT00857545 | Saponin-based immunoadjuvant OBI-821 | Polyvalent antigen-KLH conjugate vaccine | Ovarian epithelial cancer/Fallopian tube cancer/Peritoneal cancer | Completed | II |
‒Not applicable.