A, The primary outcome was survival without severe disability, defined as a score of 0 to 4 in the modified Rankin Scale (mRS) score at 6 months after admission in both treatment groups. For definition of the scores, see the Table 1 footnotes.
B, Product-limit survival estimates after admission to intensive care unit (ICU) during follow-up for both groups in the full analysis set. For early tracheostomy, the median observation time was 181 days (IQR, 61-194 days) and standard tracheostomy, 183.5 days (IQR, 93-194 days). Censored patients are indicated on the Kaplan-Meier curve by a vertical line.