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. 2020 Aug 10;52(6):1050–1059. doi: 10.1017/S0033291720002779

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© The Author(s) 2020

This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Fig. 1. — ICV, TBV, global brain structural volumes and total surface area estimate in health controls (HC) and patients within the schizophrenia spectrum (SZ) and bipolar disorder spectrum (BD), unadjusted for ICV. Top panels: Absolute ICV and TBV corrected means were significantly decreased in all adult participant subgroups that had experienced asphyxia at birth. Middle panels: Cortical and subcortical gray matter corrected volumes were significantly decreased in all adult participant subgroups that had experienced asphyxia at birth. Bottom panel: Cortical white matter volume and total surface area values were significantly decreased in all adult participant subgroups that had experienced asphyxia at birth. Main effect of asphyxia was significant at p < 0.05 for cortical white matter volume, and all other values had a significance of p < 0.005. Measures were corrected for age and sex. Error bars = standard error of mean. ** p < 0.005, * p < 0.05.