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. Author manuscript; available in PMC: 2022 Aug 1.
Published in final edited form as: Gastroenterology. 2021 Apr 20;161(2):508–521.e7. doi: 10.1053/j.gastro.2021.04.013

Figure 2.

Figure 2.

Comparison of microbial and ARG changes before and after rifaximin. (A) Volcano plot of DESeq2 lineage of bacterial species compared between pre- (orange) and post-rifaximin (purple). (B) Volcano plot of Kruskal-Wallis comparison of resistomes that changed between pre- (orange) and post-rifaximin (purple) showing higher Klebsiella oxytoca pre, which was not found post-rifaximin. (C) Volcano plot of Kruskal-Wallis comparison of ARO terms that changed between pre- (orange) and post-rifaximin (purple) showing no significant change between the time-points. (D) Volcano plot of Kruskal-Wallis comparison of AMR gene families that changed between pre- (orange) and post-rifaximin (purple) showed reduction in baseline AMR gene expressions after rifaximin.