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. 2021 Nov 9;12(3):1305–1321. doi: 10.1016/j.apsb.2021.11.002

Figure 6.

Figure 6

Effects of RG108 on ROS production and mitochondrial functions in HEI-OC1 cells after cisplatin injury. (A)–(C) Representative images and quantitative changes of Cellrox green in HEI-OC1 cells from each group. (D)–(F) Representative images and quantitative changes of Mitosox-red in HEI-OC1 cells from each group. (G)–(I) Representative images and quantitative changes of Rhodamine 123 in HEI-OC1 cells from each group. (J)–(L) Representative images and quantitative changes of TMRM in HEI-OC1 cells from each group. Scale bar = 10 μm. (M)–(R) Seahorse mitochondrial function assay. The data shown are representative of three independent seahorse runs. Data are shown as mean ± SEM. ∗P < 0.05, ∗∗P < 0.01, ∗∗∗P < 0.001, ∗∗∗∗P < 0.0001 vs. Con; #P < 0.05, ###P < 0.001, ####P < 0.0001 vs. Cis.