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. 2022 Apr 21;42(4):BSR20211841. doi: 10.1042/BSR20211841

Figure 2. Pharmacological targeting of β-catenin AML.

Figure 2

Summary of the attempted and theoretical strategies used to therapeutically target oncogenic β-catenin stability an activity in AML cells. Compound abbreviations = CWP; CWP232291, CGP; CGP049090, PFK; PFK115-584, ICG; ICG-001, PRI; PRI-274, 5-AZA; 5-Aza-2′-deoxycytidine, PROTAC; Proteolysis-Targeting Chimaeras, MSAB; methyl 3-{[(4-methylphenyl)sulfonyl]amino} benzoate, SOR; Sorafenib, QUI; Quizartinib (created using Biorender).