Studies of reaction conditions^a.

Entry	Solvent	Catalyst amount (mol%)	Oxidant	Yieldb (%)
1	Chlorobenzene	5	DTBP	54
2	Heptane	5	DTBP	22
3	Toluene	5	DTBP	83
4c	Toluene	5	DTBP	17
5	Toluene	0	DTBP	4
6	Toluene	1	DTBP	21
7	Toluene	3	DTBP	51
8	Toluene	7	DTBP	87
9	Toluene	5	K2S2O8	8
10	Toluene	5	AgNO3	11
11	Toluene	5	Oxygen	2
12d	Toluene	5	TBHP	55

^aReaction conditions: acetophenone oxime acetate (0.6 mmol), phenylacetic acid (0.2 mmol), solvent (2 mL), oxidant (0.6 mmol), at 140 °C under air for 2 h and under argon for 6 h.

^bGC yield.

^cReaction at 120 °C.

^dTBHP in water. DTBP = di-tert-butylperoxide, TBHP = tert-butyl hydroperoxide.