Table 5.
Reported optical probes for human NQOs.
Enzyme | No. | Substrate | Metabolite | Km (μmol/L) | Vmax (μmol/min/mg) | λex/λem (nm) | Ref. |
---|---|---|---|---|---|---|---|
NQO1 | NQO1-F1 | ![]() |
![]() |
23.7 | 2.14 | 485/520 | 67 |
NQO1 | NQO1-F2 | ![]() |
![]() |
13.9 | 3.14 | 585/624 | 68 |
NQO1 | NQO1-F3 | ![]() |
![]() |
3.77 | 0.24 | 374/490 | 69 |
NQO1 | NQO1-F4 | ![]() |
![]() |
2.17±0.46 | 4.01 | 410/540 | 191 |
NQO1 | NQO1-F5 | ![]() |
![]() |
14.6 | Vmax=0.9 μmol/min/L | 360/502 | 72 |
NQO1 | NQO1-F6 | ![]() |
![]() |
10.68 | 0.962 | 400/520 | 73 |
NQO1 | NQO1-F7 | ![]() |
![]() |
5.06 ± 1.31 | 101.5 | 360/450 | 74 |
NQO1 | NQO1-F8 | ![]() |
![]() |
N.A. | N.A. | 670/710 | 75 |
NQO1 | NQO1-F9 | ![]() |
![]() |
1.42 ± 0.18 | 1.89 | 730/800 | 75 |
NQO1 | NQO1-F10 | ![]() |
![]() |
3.73 | 1.22 | 680/704 | 76 |
NQO1 | NQO1-F11 | ![]() |
![]() |
1.80 ± 0.37 | 0.267 | 345/540 | 70 |
NQO1 | NQO1-F12 | ![]() |
![]() |
3.79 | Vmax=0.126 μmol/min/L | 397/600 | 77 |
NQO1 | NQO1-F13 | ![]() |
![]() |
N.A. | N.A. | 444/561 | 78 |
NQO1 | NQO1-F14 | ![]() |
![]() |
33.82 ± 0.45 | 0.00419 | 460/646 | 79 |
NQO1 | NQO1-F15 | ![]() |
![]() |
6.82 | 197.76 | 470/550 | 80 |
NQO1 | NQO-F16 | ![]() |
![]() |
6.77 | Vmax=0.043 μmoL/min/L | 510/585 | 84 |
NQO1 | NQO1-F17 | ![]() |
![]() |
10.4 | 0.00225 | 440/525 | 83 |
NQO1 | NQO1-F18 | ![]() |
![]() |
1.1 ± 0.5 | 0.31 | 606/755 | 82 |
NQO1 | NQO1-F19 | ![]() |
![]() |
N.A. | N.A. | 435/490 | 192 |