. 2022 May 3;18:17448069221097760. doi: 10.1177/17448069221097760

Table 2.

Overlaps between the gouty mice RNAseq and human GWAS of gout, corresponding statistics of DEGs are bold, underlined and italic.

	Ankle joint		DRG		SC
Symbol	log₂FC	p-value	log₂FC	p-value	log₂FC	p-value
ATXN2	−0.03389	0.81245	*−0.63983*	*0.00000*	−0.02006	0.82734
CNIH2	*−0.96389*	*0.02244*	−0.21701	0.12839	0.13911	0.31001
CUX2	0.01525	0.97320	*−0.70206*	*0.00000*	−0.08247	0.44834
HLF	*−1.86339*	*0.00000*	−0.01119	0.98194	−0.08137	0.45980
IGF1R	*0.77819*	*0.00000*	−0.07880	0.44310	0.12685	0.23950
INHBB	*0.94277*	*0.00000*	−0.14309	0.36845	−0.17877	0.28079
KCNQ1	*−1.42708*	*0.00067*	−0.07852	0.80479	−0.31812	0.37203
NIPAL1	*−1.52108*	*0.00000*	0.27202	0.35190	−0.19287	0.65037
NRXN2	*−1.71093*	*0.00002*	*−1.07030*	*0.00000*	0.16269	0.03693
PRKAG2	*−0.58726*	*0.00001*	−0.29779	0.00042	0.08028	0.42038
SLC2A9	*−1.05144*	*0.00012*	−0.56304	0.02822	0.06642	0.88348
STC1	*1.52280*	*0.00000*	*2.75347*	*0.00002*	*0.83847*	*0.00560*
UBE2Q2	*1.04378*	*0.00000*	−0.10197	0.36463	−0.05931	0.53433
VEGFA	*0.85048*	*0.00000*	−0.06485	0.64870	−0.56125	0.00000

The GWAS loci not shared with DEGs of the gouty mice RNAseq are listed as below.

A1CF, ABCG2, ACVR1BACVRL1, B3GNT4, BAZ1B, BCAS3, FAM35A, GCKR, HIST1H2BF-HIST1H4E, HNF4G, INHBC, MAF, NFAT5, PDZK1, RFX3, RREB1, SFMBT1, SLC16A9, SLC17A1, SLC22A11, SLC22A12, TMEM171, TRIM46.