Experimental design layout and observed response (y) for the DSD.

Run	X 1	X 2	X 3	X 4	X 5	X 6	X 7	X 8	X 9	Y (%)
1	18	1	4	20	9	0	10	1.5	50	66.89
2	6	5	2	20	5	10	25	1.5	50	60.47
3	18	1	2	40	7	10	40	1.5	150	62.96
4	12	3	4	30	7	5	25	1	100	72.97
5	6	3	2	40	9	0	40	0.5	50	58.96
6	18	1	2	20	5	5	40	0.5	50	53.11
7	6	1	6	20	5	0	40	1	150	33.07
8	12	1	6	40	5	10	10	0.5	50	47.20
9	18	5	6	40	5	0	40	1.5	50	60.90
10	6	1	2	20	9	10	10	0.5	150	51.93
11	18	5	2	40	9	10	10	1	50	93.05
12	6	1	2	40	5	0	10	1.5	100	53.32
13	18	5	6	20	9	10	40	0.5	100	59.47
14	6	5	6	40	9	5	10	1.5	150	59.53
15	18	1	6	40	9	0	25	0.5	150	53.90
16	18	3	6	20	5	10	10	1.5	150	68.65
17	12	5	2	20	9	0	40	1.5	150	68.04
18	18	5	2	30	5	0	10	0.5	150	87.98
19	6	5	4	40	5	10	40	0.5	150	51.33
20	6	1	6	30	9	10	40	1.5	50	37.39
21	6	5	6	20	7	0	10	0.5	50	53.66