Figure 2. DEG analysis between 9- and 26-month-old OHCs.

(A) Heatmap of differentially expressed genes.
(B) Volcano plot of DEGs. Some top DEGs are labeled. Some of the top differentially expressed genes as well as several genes known to be related to HC function are indicated.
(C) Gene set enrichment analysis of biological processes involving the top 500 up- and downregulated genes. Numeric value on the right of the panel represents the number of genes in each category.