Fig. 7.

The cancer-promoting effect of miR-5003-3p in cervical cancer can be reversed by OGN. HeLa cells were transfected with mimics NC, miR mimics, miR mimics + oe-NC or miR mimics + oe-OGN for subsequent detection. a-b. The expression of miR-5003-3p and OGN in each group was tested by qRT-PCR. c-g. CCK-8, EdU and colony formation assays were used to detect the proliferation ability of each group of cells. Scale bar, 50 μm. h-i. Wound healing assays determined the migration ability of each group of cells. Scale bar, 100 μm. j-k. Transwell invasion assays detected the invasion ability of each group of cells. Scale bar, 50 μm. **p < 0.01, ***p < 0.001