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. 2022 Apr 21;12:883543. doi: 10.3389/fonc.2022.883543

Table 4.

Baseline characteristics of the patients with lung nodules.

Malignant lung nodules (n = 459) Benign lung nodules (n = 285) P value
Size of lesions, n (%) <0.001
 φ≤8 mm 83 (18.1) 116 (40.7)
 8 mm <φ≤20 mm 271 (59.0) 133 (46.7)
 20 mm <φ≤30 mm 105 (22.9) 36 (12.6)
Number of nodules, n (%) 0.103
 Single 260 (56.7) 144 (50.5)
 Multiple 199 (43.3) 141 (49.5)
Composition, n (%) <0.001
 GGO 41 (8.9) 26 (9.1)
 pGGN 103 (22.4) 21 (7.3)
 mGGN 214 (46.6) 15 (5.2)
 Solid 101 (22.0) 223 (78.2)
Pathologic type, n (%)
 Adenocarcinoma 312 (68.0)
 SCC 39 (8.5)
 AIS or MIA 103 (22.4)
 Neuroendocrine 5 (1.1)
 Lung benign tumor 19 (6.7)
 AAH 141 (49.5)
 Inflammatory lung  nodules 72 (25.2)
 Other lung  nodules 53 (18.6)
Stage of lung cancer, n (%)
 0 (AIS) 43 (9.3)
 I 302 (65.8)
 II 51 (11.1)
 III 31 (6.8)
 IV 32 (7.0)
Imaging features <0.001
 Vessel sign 361 (78.6) 24 (8.4)
 Spiculation sign 179 (39.0) 42 (14.7)
 Lobulated sign 207 (45.1) 51 (17.9)
 Pleural indentation 154 (33.6) 37 (13.0)
 Bubble-like sign 93 (20.2) 26 (9.1)