Table 1.

Classification of autoimmune polyglandular syndromes

PAS type	Characteristics
Juvenile
Type I	Chronic candidiasis, chronic hypoparathyroidism, and Addison’s disease (at least two present)
Adult
Type II	Addison’s disease (always present), autoimmune thyroid disease and/or diabetes mellitus Type I
Type III	Autoimmune thyroid disease associated with another autoimmune disease (excluding Addison’s disease and/or hypoparathyroidism)
IIIA	APS Type III + endocrine diseases
IIIB	APS Type III + gastrointestinal or hepatic autoimmune diseases
IIIC	APS Type III + skin or neuromuscular or nervous system autoimmune diseases
IIID	APS Type III + collagen diseases, vasculitis, or hematologic autoimmune diseases
Type IV	Combinations of glandular autoimmune diseases that are not included in the previous groups