Skip to main content
. 2022 Apr 4;14(2):41–48. doi: 10.4103/ijt.ijt_59_21

Table 1.

Mechanism of action by which smoking causes hair loss

Mechanism of action
 Vasoconstrictor action by smoke metabolites
 Retention of DNA adducts causing DNA damage
 Oxidative stress and disequilibrium of antioxidant system
 Sustained microinflammation causing perifollicular fibrosis
 Desensitization of nicotinic acetylcholine receptors
 Androgen-dependent hair thinning