Supplementary Table 1.
Basic characteristics and TEG parameters of study participants before matching.
| Controls (n=2375) | CHD (n=51) | Ischemic stroke (n=34) | |
|---|---|---|---|
| Age (years) | 49.6±10.5 | 61.5±10.7* | 63.2±9.8* |
| Male (%) | 1571 (66.1%) | 38 (74.5%) | 27 (79.4%) |
| Current smoker (%) | 697 (29.3%) | 16 (31.4%) | 12 (35.3%) |
| BMI (kg/m2) | 24.5±3.2 | 25.6±3.2* | 25.2±2.5 |
| Medical history | |||
| Diabetes mellitus (%) | 194 (8.2%) | 10 (19.6%)* | 11 (32.4%)* |
| Hypertension (%) | 793 (33.4%) | 34 (66.7%)* | 21 (61.8%)* |
| Medication history | |||
| Antiplatelet drug (%) | 33 (1.4%) | 21 (41.2%)* | 4 (11.8%)* |
| Lipid-lowering drug (%) | 105 (4.4%) | 27 (52.9%)* | 11 (32.4%)* |
| Routine laboratory test | |||
| ESR (mm/h) | 4.0 (2.0, 7.0) | 4.0 (2.0, 7.5) | 4.5 (2.0, 10.0) |
| Hemoglobin (g/L) | 149.0 (137.0, 158.0) | 146.0 (138.0, 156.5) | 147.5 (140.2, 157.5) |
| WBC count (109/L) | 5.6 (4.8, 6.5) | 5.9 (4.9, 6.6) | 5.7 (4.7, 6.9) |
| HDL-C (mmol/L) | 1.2 (1.0, 1.4) | 1.1 (1.0, 1.2)* | 1.2 (1.0, 1.4) |
| LDL-C (mmol/L) | 2.9±0.8 | 2.3±0.7* | 2.9±1.3 |
| Total cholesterol (mmol/L) | 4.6±0.9 | 3.8±0.9* | 4.5±1.4 |
| Triglyceride (mmol/L) | 1.3 (0.9, 1.9) | 1.2 (0.9, 1.8) | 1.4 (1.0, 2.2) |
| Platelet parameters | |||
| Platelet count (109/L) | 228.3±55.1 | 213.2±49.4* | 207.1±9.7* |
| Platelet volume (fL) | 10.8±1.0 | 10.8±0.9 | 10.8±1.0 |
| Platelet volume distribution width (fL) | 13.3±2.3 | 13.3±2.0 | 13.2±2.5 |
| Platelet hematocrit (%) | 0.2±0.1 | 0.2±0.0* | 0.2±0.0* |
| TEG parameters | |||
| R (min) | 5.7 (5.0, 6.3) | 5.4 (4.8, 6.6) | 5.5 (4.8, 6.0) |
| K (min) | 1.5 (1.2, 1.8) | 1.5 (1.2, 1.7) | 1.4 (1.2, 1.7) |
| Angle (degree) | 73.5 (71.0, 75.6) | 73.1 (71.7, 75.8) | 74.2 (72.5, 75.6) |
| MA (mm) | 60.8±4.8 | 61.6±4.1 | 60.6±4.0 |
Continuous variables were described as mean±standard deviation or median (interquartile range) and categorical variables were presented as n (percentages). BMI – body mass index; CHD – coronary heart disease; ESR – erythrocyte sedimentation rate; HDL-C – high-density lipoprotein cholesterol; K – kinetic time; LDL-C – low-density lipoprotein cholesterol; MA – maximum amplitude; R – reaction time; WBC – white blood cell.
*
p<0.05 compared to the control group.