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. Author manuscript; available in PMC: 2022 May 4.
Published in final edited form as: ACS Chem Neurosci. 2018 Oct 17;10(4):1986–1991. doi: 10.1021/acschemneuro.8b00272

Figure 4.

Figure 4.

(a) Effects of raclopride and saline on tail pinch induced DA release in rat nucleus accumbens. (b) The comparison of ethanol effects on accumbal DA release evoked by the electrical stimulation of the VTA and tail pinch exposure. Anesthetized rats received a tail pinch or electrical stimulation of the VTA every 10 min until a stable baseline of DA release was established (at least 3 recordings with no more than 10% variance). Immediately following the last baseline recording, an intraperitoneal injection of saline, 2 g/kg ethanol, or 2 mg/kg raclopride was given. DA response was recorded for at least 1 h post injection. Data are presented as mean ± SEM n = 5 rats for each tail pinch group and n = 4 rats for electrical stimulation. **p < 0.01, ***p < 0.001.