Table 3.
PERMANOVA Table.
| Source | Degrees of freedom | Sums of Squares | R2 | F ratio | p-value |
|---|---|---|---|---|---|
| BMI Group | 1 | 0.563 | 0.0044 | 2.39 | 0.035 |
| Ethnicity/Race | 3 | 2.223 | 0.0173 | 3.14 | 0.001 |
| Annual Income | 5 | 1.610 | 0.0125 | 1.37 | 0.093 |
| Age | 1 | 0.269 | 0.0021 | 1.14 | 0.325 |
| Nulliparity Status | 1 | 2.081 | 0.0162 | 8.82 | 0.001 |
| Contraception | 1 | 0.212 | 0.0017 | 0.90 | 0.469 |
| PCOS Status | 2 | 0.415 | 0.0032 | 0.88 | 0.566 |
| Sexual Partners | 1 | 0.328 | 0.0026 | 1.39 | 0.227 |
| Douching | 1 | 0.159 | 0.0012 | 0.67 | 0.673 |
| BV Status | 2 | 0.915 | 0.0071 | 1.94 | 0.023 |
| Error | 478 | 112.693 | |||
| Total | 496 | 128.530 |
Microbiome profiles are shown to be different among healthy weight (HW) and overweight/obesity (Ow/Ob) groups (p=0.035) when adjusting for other demographic and gynecological variables. Microbiome profiles also differ based on ethnicity/race (p=0.001), nulliparity status (p=0.001), and history of bacterial vaginosis (p=0.023).