Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Schematic diagram of TBs-C inhibiting human NSCLC cells in vitro and in vivo. In vitro, TBs-C is capable of increasing autophagic flux, inhibiting cell proliferation, enhancing apoptosis, and inducing G1 cell cycle arrest via the PI3K/AKT/mTOR pathway and AKT/p21 axis. In vivo, TBs-C enhances autophagy and inhibits tumor growth by downregulating the PI3K/AKT/mTOR pathway without causing cardiac, brain, or kidney toxicity.
