Cladograms of pneumococcal and VGS parC (a), parE (b), gyrA (c), and gyrB (d) QRDR nucleotide sequences. QRDRs are as follows: parC, 322 bp encoding residues 49 to 155; parE, 185 bp encoding residues 429 to 489; gyrA, 318 bp encoding residues 55 to 160; gyrB, 430 bp encoding residues 375 to 517. VGS species are indicated as follows: O, S. oralis; S, S. sanguis; M, S. mitis.