Table 2.
The effect of the PEARS lifestyle intervention on C3 and CRP.
| C3 | Intervention | Control | P value | ||
|---|---|---|---|---|---|
| C3 Early (mg/dl) | 174 | 156.9 (25.5) | 179 | 157.8 (27.0) | 0.78 |
| C3 Late (mg/dl) | 173 | 172.4 (26.4) | 188 | 175.5 (27.4) | 0.27 |
| *p < 0.001 | *p < 0.001 | ||||
| Mean change C3 | 150 | 15.4 (18.2) | 158 | 17.0 (21.6) | 0.49 |
| CRP | |||||
| CRP Early (mg/L)a | 168 | 4.2 (11.8) | 167 | 2.6 (3.8) | 0.61 |
| CRP Late (mg/L)a | 163 | 3.4 (7.09) | 179 | 2.7 (2.9) | 0.64 |
| *p = 0.49 | *p = 0.09 | ||||
| Mean change CRPa | 139 | −0.6 (11.9) | 147 | −0.7 (5.1) | 0.65 |
Data presented as mean (standard deviation). p values derived from independent sample t-tests.
*
p value derived from paired sample t tests.
a
denotes log transformed data. C3, complement component 3; CRP- c reactive protein. Early refers to baseline bloods taken between 14 and 16 weeks and late refers to bloods taken at 28 weeks’ gestation.