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. Author manuscript; available in PMC: 2022 May 4.
Published in final edited form as: Cytokine. 2021 Oct 23;149:155748. doi: 10.1016/j.cyto.2021.155748

Table 3.

C3 and CRP concentrations according to pregnancy complications.

C3 (mg/dl) GDM P PET or PIH P
Diagnosed
 Not diagnosed
 Diagnosed
 Not diagnosed
n Mean (SD) n Mean (SD) n Mean (SD) n Mean (SD)
Early 49 167.0 (28.2) 280 156.0 (25.7) 0.01 17 141.8 (25.1) 293 157.7 (26.2) 0.02
Late 49 184.5 (33.7) 303 172.7 (25.4) 0.02 20 164.3 (24.9) 298 174.8 (27.6) 0.10
Mean change C3 CRP (mg/L) 45 16.8 (18.2) 254 16.3 (20.5) 0.87 16 16.7 (17.1) 259 16.1 (20.7) 0.90
Earlya 47 6.11 (16.2) 265 3.06 (7.1) 0.61a 16 3.7 (7.6) 279 3.5 (9.5) 0.93a
Latea 47 4.1 (10.0) 288 2.89 (4.2) 0.52a 18 3.6 (3.5) 283 3.0 (5.8) 0.18a
Mean change CRP 43 0.1 (12.8) 236 −0.4 (8.4) 0.74 14 −0.8 (7.8)00 241 −0.3 (9.6) 0.82
*

P value derived from independent sample t-tests.

a

denotes p value generated using log transformed data. C3, complement component 3; CRP- c reactive protein. GDM, gestational diabetes; PET, Pre-eclampsia; PIH, pregnancy induced hypertension. Early refers to baseline bloods taken between 14 and 16 weeks and late refers to bloods taken at 28 weeks’ gestation. Data from both the intervention and control group are used.