Table 5.
Maternal C3 and CRP concentrations in early and late pregnancy and birth outcome.
| C3 (mg/dl) | Gestational age (weeks) | p | SGA (BW< <10th centile) | p | SGA (BW < 5th centile) | p | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| < 37/40 |
>37/40 |
SGA |
Not SGA |
SGA | Not SGA | ||||||||||
| n | Mean (SD) | n | Mean (SD) | n | Mean (SD) | n | Mean (SD) | n | Mean (SD) | n | Mean (SD) | ||||
| Early | 17 | 148.7 (18.4) | 324 | 158.0 (26.7) | 0.06 | 19 | 137.0 (28.9) | 307 | 158.7 (25.6) | <0.01 | 9 | 138.5 (36.9) | 317 | 158.0 (25.8) | 0.03 |
| Late | 14 | 169.9 (21.8) | 337 | 174.4 (27.1) | 0.54 | 20 | 160.3 (33.7) | 318 | 175.8 (26.3) | 0.01 | 9 | 159.2 (41.3) | 329 | 175.3 (26.3) | 0.05 |
| Mean change C3 CRP (mg/L) | 13 | 18.5 (20.2) | 286 | 16.1 (20.2) | 0.68 | 16 | 21.6 (20.3) | 270 | 16.6 (20.2) | 0.34 | 7 | 22.3 (24.0) | 279 | 16.7 (20.2) | 0.47 |
| Earlya | 17 | 2.1 (2.3) | 308 | 3.5 (9.2) | 0.80b | 18 | 2.3 (1.9) | 293 | 3.3 (7.6) | 0.62 | 9 | 2.2 (1.6) | 302 | 3.4 (7.7) | 0.98 |
| Latea | 12 | 3.3 (3.0) | 321 | 3.0 (5.5) | 0.19b | 18 | 1.6 (1.6) | 302 | 3.0 (5.2) | 0.41 | 7 | −0.1 (0.7) | 313 | 3.1 (5.3) | 0.52 |
| Mean change CRP | 11 | 1.1 (3.5) | 268 | −0.4 (9.3) | 0.62 | 14 | −0.8 (2.2) | 252 | −0.3 (9.6) | 0.86 | 6 | −9 (1.5) | 260 | −0.3 (9.5) | 0.88 |
P values calculated by independent sample t-tests.
a
denotes log transformed data. C3, complement factor 3; CRP, c- reactive protein. BW birthweight; SGA small for gestational age.