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. 2019 Aug 21;9(45):26252–26262. doi: 10.1039/c9ra05214c

Chemical composition of bone (wt%).

Inorganic Phase Organic Phase
HA ≈ 60 Collagen≈20
H2O ≈ 9 Noncollagenous proteins≈3
Carbonate ≈ 4 Traces: polysaccharides, lipids, and cytokines
Citrate ≈ 0.9 Primary bone cell: osteoblasts, osteocytes, and osteoclasts
Na+ ≈ 0.7
Mg2+ ≈ 0.5
Cl
Others: K+, F, Zn2+, Fe2+,Cu2+,Sr2+, and Pb2+