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. 2022 May 4;17(1):447–454. doi: 10.1515/biol-2022-0047

Figure 1.

Figure 1

Effects of NR4A1 on EMT-related genes in HSC-T6 cells. The mRNA levels of E-cadherin in the acetaldehyde group were significantly downregulated, whereas FN, FSP-1, vimentin, α-SMA, and COL1A1/COL1A2 were significantly upregulated. The mRNA levels of E-cadherin in the NR4A1 activation group were significantly upregulated, while FN, FSP-1, vimentin, α-SMA, and COL1A1/COL1A2 were significantly downregulated. The mRNAs were analyzed by qRT-PCR analysis. *P < 0.05, **P < 0.01 vs control, # P < 0.05, ## P < 0.01 vs acetaldehyde. n = 3/group.