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. 2022 May 4;17(1):447–454. doi: 10.1515/biol-2022-0047

Figure 4.

Figure 4

mRNA levels of the components of the TGF-β–Smad–ZEB signal pathway in HSC-T6 cells. The mRNA levels of TGF-β, Smad2/3/4, and ZEB were significantly upregulated, while Smad7 mRNA levels were significantly downregulated. The mRNA levels of Smad7 in the NR4A1 activation group were significantly upregulated, while those of TGF-β, Smad2/3/4, and ZEB were significantly downregulated. *P < 0.05, **P < 0.01 vs control, # P < 0.05, ## P < 0.01 vs acetaldehyde. n = 3/group.